In addition to my academic and clinical roles, I aim to facilitate the application of advanced computational methods to high-value tasks throughout biomedicine.
I provide guidance at the technical intersection of machine learning, molecular biology, and clinical medicine. Typically, this occurs during prototyping and pipeline build-out for development teams or during due diligence for investors.
Prior collaborations have included:
Providing technical due diligence on investment opportunities in long-read sequencing technology.
Modeling how the composition of a somatic polygenic diagnostic panel affects power and endpoint considerations in oncology clinical trials.
Product-market fit analysis for a portable electronic health record product.
Evaluating obstacles to implementing observational study workflows in claims data.
Prototype guidance for development of a protein mutation effect prediction pipeline.
Technologies and practices
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Graph neural networks
Embedding space analysis
Tensor factorization
Knowledge graph construction
Statistical network analysis
Object detection
Fine-tuning methods
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Deep mutational scanning
RNAseq
Single-cell RNA sequencing
Long-read sequencing
CRISPR knockout and activation screening
Mass spectrometry proteomics
Pathway analysis
Spatial transcriptomics
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Electronic health records
ICD coding
Billing standards
Clinical decision-support systems
Patient recruitment
Medication nonadherence
Drug-drug interactions
Telemedicine practices
Surgical staffing
Polygenic risk scores
Clinical trial stratification
Propensity score matching